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Elevated oxalate-related markers may be associated with increased oxidative stress or altered mineral handling in susceptible individuals, particularly in the context of gut dysfunction

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MTP opening dissipates the impermeability of the mitochondrial inner membrane (MIM) allowing the transfer of solutes into the matrix, causing secondarily the rupture of the mitochondrial outer membrane (MOM)

Found in virtually every single cell of the human body, it serves as the primary intracellular defense mechanism against oxidative damage